| Citation | Jiang M, Ryu J, Kiraly M, Duke KK, Reinke V, Kim SK. Genome-wide analysis of developmental and sex-regulated gene expression profiles in Caenorhabditis elegans. Proc Natl Acad Sci U S A, 2001. |
| PubMed ID | 11134517 |
| Short Description | Genome-wide analysis of developmental and sex-regulated gene expression profiles in Caenorhabditis elegans. GEO Record: GSE3633 Platform: GPL3096 GPL3097 GPL3098 Download gene-centric, log2 transformed data: WBPaper00004489.ce.mr.csv |
| # of Conditions | 7 |
Full Description
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We have constructed DNA microarrays containing 17,871 genes, representing about 94% of the 18,967 genes currently annotated in the Caenorhabditis elegans genome. These DNA microarrays can be used as a tool to define a nearly complete molecular profile of gene expression levels associated with different developmental stages, growth conditions, or worm strains. Here, we used these full-genome DNA microarrays to show the relative levels of gene expression for nearly every gene during development, from eggs through adulthood. These expression data can help reveal when a gene may act during development. We also compared gene expression in males to that of hermaphrodites and found a total of 2,171 sex-regulated genes (P < 0.05). The sex-regulated genes provide a global view of the differences between the sexes at a molecular level and identify many genes likely to be involved in sex-specific differentiation and behavior. Experimental Details: cgc4489_adult cgc4489_egg cgc4489_L1 cgc4489_L2 cgc4489_L3 cgc4489_L4 cgc4489_male_herm. |
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